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    • Research

      Synthetic biology can be defined as the artificial (re)design of biological components and/or systems for practical applications. The technology is routed in the field of genetic engineering but draws inspiration from a variety of disciplines, such as biotechnology, chemistry, and even computer sciences. In that light, three research groups of Ghent University have decided to join forces and establish the multidisciplinary Centre for Synthetic Biology (CSB). Their common goal is to develop new processes for the production of value-added compounds, with emphasis on tailor-made carbohydrates, flavonoids and glycolipids.

        

        

      Enzyme engineering

      nature's chemists

      The group of Prof. Desmet specializes in the semi-rational design of new enzymes. They create improved biocatalysts to enable more efficient pathways or to gain access to alternative products. These enzymes can also be used in vitro to replace traditional chemical synthesis. More...

      Metabolic engineering

      microbes@work

      The group of Prof. De Mey specializes in the manipulation of cellular pathways. They develop novel tools for genetic engineering and apply these to microbial hosts. In that way, so-called designer bugs are created for the conversion of renewable resources into useful products. More...

      Membrane transport engineering

      crossing the barrier

      The group of Prof. Van Bogaert specializes in facilitating transport across cellular membranes. Understanding and exploiting the mechanisms by which molecules are transported in and out of cells is essential for the intensification of new processes in the field of synthetic biology. More...

    • Team

    • Group leaders

      Prof. Marjan De Mey

      Prof. Tom Desmet

      Prof. Inge Van Bogaert

      Coordination

      Dr. Dominique Delmeire (adm)

      Gilles Velghe (lab)

      PostDoc

      Dr. Koen Beerens

      Dr. Brecht De Paepe

      Dr. Jorick Franceus

       

      Researchers

      Dries Duchi

      Zacharie Paquet

      Enia Vande Vyvere

      External Members

      Prof. Yves Briers

      Prof. Tim De Meyer

      Prof. Wim Van Criekinge

      Prof. Alain Goossens (VIB)

      Prof. Eveline Peeters (VUB)

      PhD Students

      Carlos Alvarez Quispe

      Jim Clauwaert

      Silke Claus

      Shari Dhaene

      Matthieu Da Costa

      Emma De Beul

      Marc De Doncker

      Lien De Wannemaeker

          

      Wouter Demeester

      Chiara Guidi

      Liam Jenkins

      Sylwia Jezierska

      José López

      Jolien Lormans

      Rike Mey

      Liv Muth

         

      Andries Peeters

      Sofie Snoeck

      Bob Van Hove

      Ulrike Vogel

      Zorica Ubiparip

    • Services

      Microbial fermentation - up to 30L with complete process control and data acquisition

      Enzyme production - cloning and recombinant expression in E. coli or Pichia pastoris

      Biosurfactant production - various (modified) glycolipids with Starmorella bombicola

      Carbohydrate production - custom synthesis of special sugars and derivatives at gram scale

      Carbohydrate analysis - with chromatographic (HPAEC-PAD) and/or spectroscopic techniques

      Biocatalytic application - implementation of (commercial) enzymes in chemical synthesis

      We have also developed various tools for Synthetic Biology: you can find the list at GitHub.

    • Contact

       

       

      Coupure Links 653, Building B

      BE-9000 Ghent, Belgium

      +32 (0)9 264 6028

      csb@ugent.be

       

      @CSB_UGent

       

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