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  • Research

    Synthetic biology can be defined as the artificial (re)design of biological components and/or systems for practical applications. The technology is routed in the field of genetic engineering but draws inspiration from a variety of disciplines, such as biotechnology, chemistry, and even computer sciences. In that light, three research groups of Ghent University have decided to join forces and establish the multidisciplinary Centre for Synthetic Biology (CSB). Their common goal is to develop new processes for the production of value-added compounds, with emphasis on tailor-made carbohydrates, flavonoids and glycolipids.

      

      

    Enzyme engineering

    nature's chemists

    The group of Prof. Desmet specializes in the semi-rational design of new enzymes. They create improved biocatalysts to enable more efficient pathways or to gain access to alternative products. These enzymes can also be used in vitro to replace traditional chemical synthesis. More...

    Metabolic engineering

    microbes@work

    The group of Prof. De Mey specializes in the manipulation of cellular pathways. They develop novel tools for genetic engineering and apply these to microbial hosts. In that way, so-called designer bugs are created for the conversion of renewable resources into useful products. More...

    Membrane transport engineering

    crossing the barrier

    The group of Prof. Van Bogaert specializes in facilitating transport across cellular membranes. Understanding and exploiting the mechanisms by which molecules are transported in and out of cells is essential for the intensification of new processes in the field of synthetic biology. More...

  • Team

  • PostDoc

    Dr. Koen Beerens

    Dr. Brecht De Paepe

    Dr. Lien De Wannemaeker

    Dr. Shari Dhaene

    Dr. Jorick Franceus

    Dr. Chiara Guidi

    Dr. Jungho Lee

    Dr. Simone Savino

    Dr. Aabid Shah

    Dr. Christina Stadlbauer

    Researchers

    Dries Duchi

    Zacharie Paquet

    PhD Students

    Bénédicte Amery

    Carlos Alvarez Quispe

    Tibo De Coninck

    Maria da Fonseca

    Cara Deal

    Jim Clauwaert

    Silke Claus

    Jasmine De Baets

    Emma De Beul

    Marc De Doncker

    Wouter Demeester

        

    Marte Elias

    Koen Gistelinck

    Liam Jenkins

    Laurens Lambrecht

    Babette Lamotte

    Arthur Leyder

    José López

    Jolien Lormans

    Rike Mey

    Liv Muth

    Andries Peeters

       

    Elena Lahmeyer

    Lobke Sips

    Sofie Snoeck

    Manon Steynen

    Meriam Vandeputte

    Nick Vereecke

    Ulrike Vogel

    Alex Windels

  • Services

    Microbial fermentation - up to 30L with complete process control and data acquisition

    Enzyme production - cloning and recombinant expression in E. coli or Pichia pastoris

    Biosurfactant production - various (modified) glycolipids with Starmorella bombicola

    Carbohydrate production - custom synthesis of special sugars and derivatives at gram scale

    Carbohydrate analysis - with chromatographic (HPAEC-PAD) and/or spectroscopic techniques

    Biocatalytic application - implementation of (commercial) enzymes in chemical synthesis

    High-throughput molecular cloning & screening - flexible, automated and high-throughput cloning and library screening platform for, e.g., enzyme or strain mutants and synthetic biology tools

    We have also developed various tools for Synthetic Biology: you can find the list at GitHub.

  • Contact

     

     

    Coupure Links 653, Building B

    BE-9000 Ghent, Belgium

    +32 (0)9 264 6028

    csb@ugent.be

     

    @CSB_UGent